Head & Neck Case Review 2020-12

Head & Neck Case Review

December, 2020


A boy presented to the pediatric otolaryngology clinic with a chief concern of mass in his left neck of several months’ duration.  He was also experiencing mild intermittent pain. There was no lymphadenopathy. Pre-operative imaging studies identified an intraparotid nodule.  A superficial parotidectomy was performed. H&E sections of the nodule are shown.



Q1. Which gene is most likely to harbor an alteration in this patient’s tumor?

  • A. MAML2
  • B. NR4A3
  • C. PLAG1
  • D. PTEN

Q2. This tumor type is associated with a considerable rate of recurrence.

  • A. True
  • B. False



Jiancong Liang, MD PhD
Assistant Professor
Department of Pathology, Microbiology and Immunology
Vanderbilt University Medical Center, Nashville, TN