Head & Neck Case Review
A 65 year-old male with no significant past medical history presents with fatigue, difficulty swallowing, and voice changes for several months duration. CT scan showed an 8 cm left-sided neck mass. The patient underwent left hemithyroidectomy and parathyroidectomy. CT imaging, H&E sections, and immunostains of the mass are shown.
Q1. All of the following are characteristic features of this tumor, EXCEPT:
- A. Invasive growth involving adjacent structures
- B. Vascular and/or perineural invasion
- C. Nodular growth pattern with broad bands of fibrous connective tissue
- D. Rare recurrence after resection
Q2. CDC73 mutation is the molecular driver in the pathogenesis of this tumor.
- A. True
- B. False
Mitra Mehrad, MD
Department of Pathology, Microbiology and Immunology
Vanderbilt University Medical Center, Nashville, TN