Head & Neck Case Review 2022-06

Head & Neck Case Review

June, 2022


A 61-year-old female presented with a lesion on the right maxillary gingiva. Clinical examination revealed an ulcerated and endophytic lesion with associated leukoerythroplakia, involving the right maxillary gingiva and the adjacent soft tissue with noticeable bone loss. No lymphadenopathy was noted. An incisional biopsy was performed.



1. The histologic features are suggestive of:

  • A. Malignant melanoma
  • B. Squamous cell carcinoma
  • C. Traumatic ulcerative granuloma with stromal eosinophilia
  • D. Granulomatosis with polyangiitis
  • E. Langerhans cell histiocytosis

2. True or False: The prognostic role of eosinophilic infiltration in this disease is still unknown

  • True
  • False



Saja Alramadhan, BDS, OMFP
Fellow, Department of Oral and Maxillofacial Pathology
University of Florida College of Dentistry