Head & Neck Case Review 2024-04

Head & Neck Case Review

April, 2024


A 60-year-old man presents with a slowly growing painless lesion confined to the parotid gland. Superficial parotidectomy reveals a 2.0 cm cystic mass. Histologically, this mass is a well-delineated nodule without necrosis or increased mitotic activity. The stroma is fibrotic with mild chronic inflammation but lacks a prominent lymphoid component.



1. True or False: This benign salivary gland tumor occurs exclusively in the parotid gland.

2. True or False: This salivary gland tumor is associated with germline mutations in mismatch repair genes.


Melad N. Dababneh, MBBS
Head and Neck Pathology Fellow
Cleveland Clinic

Christpher C. Griffith, MD, PhD
Associate Professor of Pathology
Cleveland Clinic Lerner College of Medicine